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  • Anticandidal Therapeutics : Discovery and Development
    Anticandidal Therapeutics : Discovery and Development

    Developments of antifungal agents have declined as compared to other antibiotics that have displayed a potent development with time.There is an urgent need for both prophylactic and therapeutic treatments worldwide to control the severity of infections caused by Candida.Anticandidal Therapeutics: Discovery and Development provides the readers with a compiled knowledge of the fungal human infection Candida and the development of anticandidal drugs.Anticandidal Therapeutics helps researchers form the basis for the discovery and development of novel anticandidal therapies.In 14 chapters this book provides collective information on anticandidal agents and their discovery and development with respect to major drug transporter families, different stages of anticandidal agent development, recent trends and progress in antifungal translational research, clinical studies status of anticandidal therapeutic agents, and drug repurposing for development of novel anticandidal agents.

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  • Cloud Computing Networking : Theory, Practice, and Development
    Cloud Computing Networking : Theory, Practice, and Development

    Cloud computing is the most significant technology transformation since the introduction of the Internet in the early 1990s.As more and more companies and educational institutions plan to adopt a cloud-based IT infrastructure, today’s job market requires IT professionals who understand cloud computing and have hands-on experience developing cloud-based networks.Cloud Computing Networking: Theory, Practice, and Development covers the key networking and system administration concepts as well as the vital hands-on skills you need to master cloud technology. This book is designed to help you quickly get started in deploying cloud services for a real-world business.It provides detailed step-by-step instructions for creating a fully functioning cloud-based IT infrastructure using the Microsoft Azure cloud platform.In this environment, you can develop cloud services collaboratively or individually.The book enhances your hands-on skills through numerous lab activities.In these lab activities, you will learn to Implement the following services in a cloud environment: Active Directory, DHCP, DNS, and Certificate ServicesConfigure Windows Server so it can route IP trafficImplement IP Security Policy and Windows Firewall with Advanced Security toolsCreate a point-to-site connection between Microsoft Azure and a local computerCreate a site-to-site connection between Microsoft Azure and an on-premises networkDevelop a hybrid cloud that integrates Microsoft Azure with a private cloud created on a local networkCloud Computing Networking: Theory, Practice, and Development includes numerous examples, figures, and screen shots to help you understand the information.Each chapter concludes with a summary of the major topics and a set of review questions.With this book, you will soon have the critical knowledge and skills to develop and manage cloud-based networks.

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  • Basic Principles of Drug Discovery and Development
    Basic Principles of Drug Discovery and Development

    Basic Principles of Drug Discovery and Development presents the multifaceted process of identifying a new drug in the modern era, which requires a multidisciplinary team approach with input from medicinal chemists, biologists, pharmacologists, drug metabolism experts, toxicologists, clinicians, and a host of experts from numerous additional fields.Enabling technologies such as high throughput screening, structure-based drug design, molecular modeling, pharmaceutical profiling, and translational medicine are critical to the successful development of marketable therapeutics. Given the wide range of disciplines and techniques that are required for cutting edge drug discovery and development, a scientist must master their own fields as well as have a fundamental understanding of their collaborator’s fields.This book bridges the knowledge gaps that invariably lead to communication issues in a new scientist’s early career, providing a fundamental understanding of the various techniques and disciplines required for the multifaceted endeavor of drug research and development.It provides students, new industrial scientists, and academics with a basic understanding of the drug discovery and development process.The fully updated text provides an excellent overview of the process and includes chapters on important drug targets by class, in vitro screening methods, medicinal chemistry strategies in drug design, principles of in vivo pharmacokinetics and pharmacodynamics, animal models of disease states, clinical trial basics, and selected business aspects of the drug discovery process.

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  • Drug Discovery and Development : Technology in Transition
    Drug Discovery and Development : Technology in Transition

    Essential insight into drug development and the pharmaceutical industry With unprecedented interest in the power that the modern therapeutic armamentarium has to combat disease, the new edition of Drug Discovery and Development is an essential resource for anyone interested in understanding how drugs and other therapeutic interventions are discovered and developed, through to clinical research, registration, and market access. The text has been thoroughly updated, with new information on biopharmaceuticals and vaccines as well as clinical development and target identification.Drug discovery and development continues to evolve rapidly and this new edition reflects important changes in the landscape. Edited by industry experts Raymond Hill and Duncan Richards, this market-leading text is suitable for undergraduates and graduates undertaking degrees in pharmacy, pharmacology, toxicology, and clinical development through to those embarking on a career in the pharmaceutical industry. Key stages of drug discovery and development Chapters outline the contribution of individual disciplines to the overall process Supplemented by specific chapters on different modalities Includes coverage of Oligonucleotide therapies; cell and gene therapy Now comes with online access on StudentConsult

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  • What is better: web development or game development?

    The answer to this question depends on individual preferences and career goals. Web development is better for those who are interested in creating websites, web applications, and working with a variety of programming languages and frameworks. On the other hand, game development is better for those who are passionate about creating interactive and immersive experiences, working with 3D graphics, and game engines. Both fields offer unique challenges and opportunities, so it ultimately comes down to personal interests and career aspirations.

  • What is development?

    Development refers to the process of improving the economic, social, and environmental well-being of a society. It involves creating opportunities for people to lead healthy, productive lives and to realize their full potential. Development can encompass various aspects such as economic growth, poverty reduction, access to education and healthcare, and sustainable use of resources. Ultimately, development aims to enhance the quality of life for all members of a community or country.

  • What is the difference between web development and software development?

    Web development primarily focuses on creating websites and web applications that are accessed through a web browser, using technologies such as HTML, CSS, and JavaScript. Software development, on the other hand, involves creating applications that can run on various platforms, including desktop computers, mobile devices, and servers. While web development is a subset of software development, software development encompasses a broader range of applications beyond just web-based ones.

  • What is the difference between software development and application development?

    Software development is a broader term that encompasses the entire process of creating software, including planning, designing, coding, testing, and maintenance. Application development, on the other hand, specifically refers to the process of creating a specific type of software application, such as a mobile app, web app, or desktop application. In other words, application development is a subset of software development, focusing on the creation of specific types of software applications.

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  • Neglected Tropical Diseases : Drug Discovery and Development
    Neglected Tropical Diseases : Drug Discovery and Development

    A drug discovery reference to the crippling tropical diseases that affect more than 1 billion people. Neglected Tropical Diseases is the first book of its kind to offer a guide that follows the World Health Organization?s list of neglected tropical diseases.The authors?all are experts on the topic?address the development of effective treatments for 12 crippling infectious diseases that affect almost 20% of the world?s popluation. The book includes information on the common approaches and the most important factors that lead to the development of new drugs for treating tropical diseases.Individual chapters review 12 neglected tropical diseases that are grouped by infectious agent, from viruses to bacteria to eukaryotic parasites.For each of these diseases, the book explains the unmet medical need and explores the current and potential drug discovery strategies.The book also includes information on potential drug compounds derived from natural products.This important book: -Ties together information from different sources for developing novel treatsments forneglected tropical diseases -Is aligned with WHO?s initiative to eradicate tropical diseases -Outlines current and potential drugs for treating tropical diseases -Provides a standard reference for the entire field Written for medicinal chemists, pharmaceutical chemists, pharmaceutical industry, virologists, parasitologists, and specialists on tropics medicine, Neglected Tropical Diseases offers an essential guide and a systematic reference for the development of successful treatments for 12 crippling infectious diseases.

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  • Contemporary Accounts in Drug Discovery and Development
    Contemporary Accounts in Drug Discovery and Development

    CONTEMPORARY ACCOUNTS IN DRUG DISCOVERY AND DEVELOPMENT A useful guide for medicinal chemists and pharmaceutical scientists Drug discovery is a lengthy and complex process that typically involves identifying an unmet medical need, determining a biological target, chemical library screening to identify a lead, chemical optimization, preclinical studies and clinical trials.This process often takes many years to complete, and relies on practitioners’ knowledge of chemistry and biology, but also—and perhaps more importantly—on experience.Improving the success rate in discovery and development through a thorough knowledge of drug discovery principles and advances in technology is critical for advancement in the field.Contemporary Accounts in Drug Discovery and Development provides drug discovery scientists with the knowledge they need to quickly gain mastery of the drug discovery process.A thorough accounting is given for each drug covered within the book, as the authors provide pharmacology, drug metabolism, biology, drug development, and clinical studies for every case, with modern drug discovery principles and technologies incorporated throughout.Contemporary Accounts in Drug Discovery and Development readers will also find Case histories used as an engaging way of learning about the drug discovery/development processDetailed biological rational and background information, drug design principles, SAR development, ADMET considerations, and clinical studiesThe full history of individual marketed small molecule drugsCoverage of drug candidates that have passed Phase I clinical trials with different modalities, such as antibody drug conjugates (ADC), proteolysis-targeting chimera (PROTAC), and peptide drugsThe application of new technologies in drug discovery such as DNA-encoded libraries (DEL), positron emission tomography (PET), and physics-based computational modeling employing free energy perturbation (FEP) Contemporary Accounts in Drug Discovery and Development is a helpful tool for medicinal chemists, organic chemists, pharmacologists, and other scientists in drug research and process development.It may be considered essential reading for graduate courses in drug discovery, medicinal chemistry, drug synthesis, pharmaceutical science, and pharmacology.It is also a useful resource for pharmaceutical industry labs, as well as for libraries.

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  • Web-Scale Discovery Services : Principles, Applications, Discovery Tools and Development Hypotheses
    Web-Scale Discovery Services : Principles, Applications, Discovery Tools and Development Hypotheses

    Web-Scale Discovery Services: Principles, Applications, Discovery Tools and Development Hypotheses summarizes and presents the state-of-the-art in WSDS.The title promotes a middle-way between finding the best tool for each particular need and the search for the most reliable systems.The title identifies basic theoretical problems and offers practical solutions for librarians.The volume offers a summary of ideas from around the world, giving a new perspective that is backed up by strong theory.Offering a vision for libraries, this book also allows archivists, museum specialists, computer scientists, commercial operators and interested users to deepen their culture and information literacy. The great number of information sources now available and the changing habits of web users has led to the development of Web Scale Discovery Services (WSDS).The goal of these systems and techniques is to make catalogues, databases, institutional repositories, Open Access archives and other databases searchable and discoverable through a single point of access.The diffusion of systems and connections between data disseminated by libraries and published by other institutions poses a challenge to understanding discovery in the modern library.

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  • Pharmacology in Drug Discovery and Development : Understanding Drug Response
    Pharmacology in Drug Discovery and Development : Understanding Drug Response

    Pharmacology in Drug Discovery and Development: Understanding Drug Response, Third Edition is an introductory resource that illustrates how pharmacology can be used to furnish the tools necessary to analyze different drug behavior and trace this behavior to its root cause or molecular mechanism of action.Chapters logically build upon one another to show how to characterize the pharmacology of any given molecule and allow for more informed predictions of drug effects in all biological systems.New chapters are dedicated to the interdisciplinary drug discovery environment in both industry and academia, and special techniques involved in new drug screening and lead optimization. The updates to the Third Edition include a new section converting “descriptive” data into “predictive” data through comparison to mathematical models, expansion on enzymes, drug metabolites and drug–drug interactions, and two new chapters.The newly developed companion website hosts further educational resources to complement the book.As in previous editions, this new edition includes numerous valuable chapter summaries, detailed references, practical examples, and case studies throughout.

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  • What is heterogeneous development?

    Heterogeneous development refers to the uneven progress or growth that occurs within a particular region or country. It means that different areas or groups within the same region experience varying levels of development, resulting in disparities in terms of income, infrastructure, education, and other socio-economic indicators. This can be due to factors such as unequal distribution of resources, historical legacies, government policies, or global economic trends. Addressing heterogeneous development often requires targeted interventions and policies to reduce disparities and promote more inclusive growth.

  • Is game development lucrative?

    Game development can be lucrative for those who are successful in creating popular and profitable games. The industry is competitive, but top developers and studios can earn significant revenue from game sales, in-game purchases, and licensing deals. However, it can also be a risky and unpredictable field, with many games failing to recoup their development costs. Overall, game development has the potential to be lucrative, but success is not guaranteed and requires a combination of talent, hard work, and market understanding.

  • What is covalent development?

    Covalent development is a term used in the context of software development to describe a collaborative approach to building and maintaining software. It involves multiple developers working together on the same codebase, using version control systems to manage changes and updates. Covalent development emphasizes communication, teamwork, and shared responsibility for the code, leading to a more efficient and cohesive development process. This approach allows for greater flexibility and adaptability in responding to changes and challenges in the development process.

  • What is higher development?

    Higher development refers to the process of personal and intellectual growth that leads to a deeper understanding of oneself and the world. It involves the cultivation of critical thinking, emotional intelligence, and moral reasoning, as well as the ability to adapt to new challenges and perspectives. Higher development also encompasses the pursuit of knowledge, wisdom, and self-actualization, leading to a more fulfilling and purposeful life.

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